D-Dimer is one of the measurable by-products of activation of the fibrinolytic system. Quantitation of D-Dimer assesses fibrinolytic activation and intravascular thrombosis. D-Dimer is of particular value in excluding the diagnosis of venous thromboembolism among patients at high risk.
D-dimer is a fragment of protein which gets produced when blood clots and eventually dissolve. There are very low levels in the blood which is often undetectable, unless there are a lot of blood clots that are formed and being broken down. D-dimers are usually used in order to determine the likelihood of clotting disorders or thrombosis and to diagnose conditions related to thrombosis, such as deep vein thrombosis and pulmonary embolism.
This test is performed in following conditions such as:
• Symptoms of thrombotic episode
• A condition which causes inappropriate blood clot formation
• If you have ever had a deep vein thrombosis or pulmonary embolism
• If you are at risk or developing or have developed disseminated intravascular coagulation (DIC)
This test is not appropriate for ruling out clotting issues for pediatric patients. Results for people undergoing anticoagulant therapy should be interpreted with caution because D-Dimer levels do not tend to increase to the same degree as in people not receiving anticoagulants. Levels can be increased in individuals with cancer, underlying inflammation, atherosclerotic vascular disease, pregnancy, and in liver disease due to decreased hepatic clearance. Levels increase with age.
Estimated Time Taken
Turnaround for this test is typically 1-3 business days.