Metanephrines, Blood (Plasma)
This is a useful test to determine the cause of persistent hypertension. The urine sample is slightly more accurate, since having blood taken can cause the hormones and metabolites to increase.
Metanephrine is a metabolite of adrenaline (one of the hormones produced by the adrenal glands- these hormones are known as catecholamines). By measuring its levels, doctors can get a clear picture of the activity of the catecholamines in the body. Catecholamines are a group of hormones that are released into the blood in times of stress. The most common catecholamines are norepinephrine and epinephrine. These are produced by the adrenal glands and cells of the sympathetic nervous system. The metabolites of these hormones can be measured in the blood. Measuring metabolites in the blood is used to determine adrenal functions since rare disorders like pheochromocytomas can cause these hormone levels to be abnormal. Therefore, this is a useful test to determine the cause of persistent hypertension. The urine sample is slightly more accurate, since having blood taken can cause these hormones and metabolites to increase.
This test is performed in following conditions such as:
• Persistent high blood pressure
• High blood pressure that does not respond to treatment
• Severe headaches
• Sweating and flushing
• Rapid heart rate
Also Known As: Normetanephrine
Avoid alcohol, coffee, tea, tobacco and strenuous exercise prior to collection. Overnight fasting is preferred. The person being tested should be in a supine position for at least 15 minutes before and during sample collection. A number of different medications may affect test results. Consult your physician before discontinuing any medications.
Estimated Time Taken
Turnaround for this test is typically 8-10 business days.